Publications of Michael J. Ziller

Boudriot, E.; Stephan, M.; Rabe, F.; Smigielski, L.; Schmitt, A.; Falkai, P.; Ziller, M. J.; Rossner, M. J.; Homan, P.; Papiol, S. et al.; Raabe, F. J.: Genetic Analysis of Retinal Cell Types in Neuropsychiatric Disorders. JAMA psychiatry (2025)

Raabe, F. J.; Hausruckinger, A.; Gagliardi, M.; Ahmad, R.; Almeida, V.; Galinski, S.; Hoffmann, A.; Weigert, L.; Rummel, C. K.; Murek, V. et al.; Trastulla, L.; Jiménez-Barrón, L.; Atella, A.; Maidl, S.; Menegaz, D.; Hauger, B.; Wagner, E.-M.; Gabellini, N.; Kauschat, B.; Riccardo, S.; Cesana, M.; Papiol, S.; Sportelli, V.; Rex-Haffner, M.; Stolte, S. J.; Wehr, M. C.; Salcedo, T. O.; Papazova, I.; Detera-Wadleigh, S.; McMahon, F. J.; Schmitt, A.; Falkai, P.; Hasan, A.; Cacchiarelli, D.; Dannlowski, U.; Nenadic, I.; Kircher, T.; Scheuss, V.; Eder, M.; Binder, E. B.; Spengler, D.; Rossner, M. J.; Ziller, M. J.: Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairment. bioRxiv: the preprint server for biology (2024)

Trastulla, L.; Dolgalev, G.; Moser, S.; Jiménez-Barrón, L.; Andlauer, T. F. M.; von Scheidt, M.; Budde, M.; Heilbronner, U.; Papiol, S.; Teumer , A. et al.; Homuth, G.; Voelzke, H.; Doerr , M.; Falkai, P.; Schulze, T. G.; Gagneur, J.; Iorio, F.; Müller-Myhsok, B.; Schunkert, H.; Ziller, M. J.: Distinct genetic liability profiles define clinically relevant patient strata across common diseases. NATURE COMMUNICATIONS 15 (1), 5534 (2024)

Cesana, M.; Tufano, G.; Panariello, F.; Zampelli, N.; Ambrosio, S.; De Cegli, R.; Mutarelli, M.; Vaccaro, L.; Ziller, M. J.; Cacchiarelli, D. et al.; Medina, D. L.; Ballabio, A.: EGR1 drives cell proliferation by directly stimulating TFEB transcription in response to starvation. PLOS BIOLOGY 21 (3), e3002034 (2023)

Matosin, N.; Arloth, J.; Czamara, D.; Edmond, K. Z.; Maitra, M.; Froehlich, A. S.; Martinelli, S.; Kaul, D.; Bartlett, R.; Curry, A. R. et al.; Gassen, N. C.; Hafner, K.; Mueller, N. S.; Worf, K.; Rehawi, G.; Nagy, C.; Halldorsdottir, T.; Cruceanu, C.; Gagliardi, M.; Gerstner, N.; Ködel, M.; Murek, V.; Ziller, M. J.; Scarr, E.; Tao, R.; Jaffe, A. E.; Arzberger, T.; Falkai, P.; Kleinmann, J. E.; Weinberger, D. R.; Mechawar, N.; Schmitt, A.; Dean, B.; Turecki, G.; Hyde, T. M.; Binder, E. B.: Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex. ACTA NEUROPATHOLOGICA 145 (4), pp. 439 - 459 (2023)

Penner-Goeke, S.; Bothe, M.; Rek, N.; Kreitmaier, P.; Poehlchen, D.; Kühnel, A.; Glaser, L. V.; Kaya, E.; Krontira, A.; Roeh, S. et al.; Czamara, D.; Ködel, M.; Monteserin-Garcia, J.; Diener, L.; Woelfel, B.; Sauer, S.; Rummel, C.; Riesenberg, S.; Arloth-Knauer, J.; Ziller, M.; Labeur, M.; Meijsing, S.; Binder, E. B.: High- throughput screening of glucocorticoid- induced enhancer activity reveals mechanisms of stress- related psychiatric disorders. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 120 (49), e2305773120 (2023)

Rummel, C.; Gagliardi, M.; Ahmad, R.; Herholt, A.; Jiménez-Barrón, L.; Murek, V.; Weigert, L.; Hausruckinger, A.; Maidl, S.; Hauger, B. et al.; Raabe, F. J.; Fuerle, C.; Trastulla, L.; Turecki, G.; Eder, M.; Rossner, M. J.; Ziller, M. J.: Massively parallel functional dissection of schizophrenia- associated noncoding genetic variants. CELL 186 (23), pp. 5165 - 5182.e33 (2023)

Chang, S.; Fermani, F.; Lao, C.-L.; Huang, L.; Jakovcevski, M.; Di Giaimo, R.; Gagliardi, M.; Menegaz, D.; Hennrich, A. A.; Ziller, M. et al.; Eder, M.; Klein, R.; Cai, N.; Deussing, J. M.: Tripartite extended amygdala-basal ganglia CRH circuit drives locomotor activation and avoidance behavior. SCIENCE ADVANCES 8 (46) (2022)

Raabe, F. J.; Stephan, M.; Waldeck, J. B.; Huber, V.; Demetriou, D.; Kannaiyan, N.; Galinski, S.; Glaser, L. V.; Wehr, M. C.; Ziller, M. J. et al.; Schmitt, A.; Falkai, P.; Rossner, M. J.: Expression of Lineage Transcription Factors Identifies Differences in Transition States of Induced Human Oligodendrocyte Differentiation. CELLS 11 (2), 241 (2022)

Yuan, W.; Ma, S.; Brown, J. R.; Kim, K.; Murek, V.; Trastulla, L.; Meissner, A.; Lodato, S.; Shetty, A. S.; Levin, J. Z. et al.; Buenrostro, J. D.; Ziller, M. J.; Arlotta, P.: Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex. NATURE NEUROSCIENCE 25 (8), pp. 1049 - 1058 (2022)

Hoffmann, A.; Ziller, M.; Spengler, D.: Focus on Causality in ESC/iPSC-Based Modeling of Psychiatric Disorders. CELLS 9 (2), 366 (2020)

Genga, R. M. J.; Kernfeld, E. M.; Parsi, K. M.; Parsons, T. J.; Ziller, M. J.; Maehr, R.: Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development. CELL REPORTS 27 (3), pp. 708 - 718 (2019)

Giulitti, S.; Pellegrini, M.; Zorzan, I.; Martini, P.; Gagliano, O.; Mutarelli, M.; Ziller, M. J.; Cacchiarelli, D.; Romualdi, C.; Elvassore, N. et al.; Martello, G.: Direct generation of human naive induced pluripotent stem cells from somatic cells in microfluidics. NATURE CELL BIOLOGY 21 (2), pp. 275 - 286 (2019)

Hoffmann, A.; Ziller, M.; Spengler, D.: Progress in iPSC-Based Modeling of Psychiatric Disorders. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20 (19), 4896 (2019)

Ahmad, R.; Sportelli, V.; Ziller, M.; Spengler, D.; Hoffmann, A.: Tracing Early Neurodevelopment in Schizophrenia with Induced Pluripotent Stem Cells. CELLS 7 (9), 140 (2018)

Cacchiarelli, D.; Qiu, X.; Srivatsan, S.; Manfredi, A.; Ziller, M. J.; Overbey, E.; Grimaldi, A.; Grimsby, J.; Pokharel, P.; Livak, K. J. et al.; Li, S.; Meissner, A.; Mikkelsen, T. S.; Rinn, J. L.; Trapnell, C.: Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome. CELL SYSTEMS 7 (3), pp. 258 - e3 (2018)

Hoffmann, A.; Sportelli, V.; Ziller, M.; Spengler, D.: From the Psychiatrist's Couch to Induced Pluripotent Stem Cells: Bipolar Disease in a Dish. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 19 (3), 770 (2018)

Hoffmann, A.; Ziller, M.; Spengler, D.: Childhood-Onset Schizophrenia: Insights from Induced Pluripotent Stem Cells. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 19 (12), 3829 (2018)

Sheng, C.; Jungverdorben, J.; Wiethoff, H.; Lin, Q.; Flitsch, L. J.; Eckert, D.; Hebisch, M.; Fischer, J.; Kesavan, J.; Weykopf, B. et al.; Schneider, L.; Holtkamp, D.; Beck, H.; Till, A.; Wuellner, U.; Ziller, M. J.; Wagner, W.; Peitz, M.; Bruestle, O.: A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation. NATURE COMMUNICATIONS 9 (1), 4047 (2018)

Hoffmann, A.; Sportelli, V.; Ziller, M.; Spengler, D.: Epigenomics of Major Depressive Disorders and Schizophrenia: Early Life Decides. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 18 (8), 1711 (2017)