Clinical Studies

Our projects focus on three main lines of research; firstly the biological mechanisms of psychotherapy, secondly the use of biomarkers to optimize the psycho- and pharmacological treatments to individual patient characteristics, and finally the differential assessment of cognitive deficits in patients with depression and the consequent individualized treatment approach. Our work is realized through close cooperation with the departments Stress Neurobiology and Neurogenetics and Translational Research in Psychiatry.
Our overall aim is to provide optimized medical care for our patients. Therefore, as part of our latest psychotherapy study, a wide spectrum of psychological and biological procedures will be carried out (e.g. cMRT, fMRT, psychophysiological paradigms, molecular genetic methods).

DetECT-Studie

Depression is one of the most common psychiatric disorders. In addition to medication and psychotherapy, electroconvulsive therapy (ECT) has long been used for treatment. Despite its proven efficacy and safety, our aim is to further improve ECT in order to more accurately predict therapeutic success and to understand the underlying mechanisms in even greater detail. [more]

BeCOME Study

Within the scope of the BeCOME study, we investigate if objective data can provide additional diagnostic information on mental disorders and if so, what kind of data. To implement this study, we are looking for outpatients and healthy controls. [more]

DECIDE

Research into a biomarker combination that predicts response to lithium in severe depression [more]

Psychotherapy Study OPTIMA