Publications of Jens Stepan

Stepan, J.; Heinz, D. E.; Dethloff, F.; Wiechmann , S.; Martinelli, S.; Hafner, K.; Ebert, T.; Junglas, E.; Haeusl, A. S.; Poehlmann, M. L. et al.; Jakovcevski, M.; Pape, J. C.; Zannas, A. S.; Bajaj , T.; Hermann, A.; Ma, X.; Pavenstaedt, H.; Schmidt, M. V.; Philipsen, A.; Turck, C. W.; Deussing, J. M.; Rammes, G.; Robinson, A. C.; Payton, A.; Wehr, M. C.; Stein, V.; Murgatroyd, C.; Kremerskothen, J.; Kuster, B.; Wotjak, C. T.; Gassen, N. C.: Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice. SCIENCE SIGNALING 17 (834), eadj6603 (2024)

Stepan, J.; Heinz, D. E.; Dethloff, F.; Bajaj, T.; Zellner, A.; Hafner, K.; Wiechmann, S.; Mackert, S.; Mecdad, Y.; Rabenstein, M. et al.; Ebert, T.; Martinelli, S.; Haeusl, A. S.; Poehlmann, M. L.; Hermann, A.; Ma, X.; Pavenstaedt, H.; Schmidt, M. V.; Philipsen, A.; Turck, C. W.; Deussing, J. M.; Kuster, B.; Wehr, M. C.; Stein, V.; Kremerskothen, J.; Wotjak, C. T.; Gassen, N. C.: Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning. CELL REPORTS 41 (10), 111766 (2022)

Stepan, J.; Anderzhanova, E.; Gassen, N. C.: Hippo Signaling: Emerging Pathway in Stress-Related Psychiatric Disorders? FRONTIERS IN PSYCHIATRY 9, 715 (2018)

Micale, V.; Stepan, J.; Jurik, A.; Pamplona, F. A.; Marsch, R.; Drago, F.; Eder, M.; Wotjak, C. T.: Extinction of avoidance behavior by safety learning depends on endocannabinoid signaling in the hippocampus. JOURNAL OF PSYCHIATRIC RESEARCH 90, pp. 46 - 59 (2017)

Stepan, J.; Hladky, F.; Uribe, A.; Holsboer, F.; Schmidt, M. V.; Eder, M.: High-Speed imaging reveals opposing effects of chronic stress and antidepressants on neuronal activity propagation through the hippocampal trisynaptic circuit. FRONTIERS IN NEURAL CIRCUITS 9, 70 (2015)

Stepan, J.; Dine, J.; Eder, M.: Functional optical probing of the hippocampal trisynaptic circuit in vitro: network dynamics, filter properties, and polysynaptic induction of CA1 LTP. Frontiers in neuroscience 9, 160 (2015)

Gassen, N. C.; Hartmann, J.; Zschocke, J.; Stepan, J.; Hafner, K.; Zellner, A.; Kirmeier, T.; Kollmannsberger, L.; Wagner, K. V.; Dedic, N. et al.; Balsevich, G.; Deussing, J. M.; Kloiber, S.; Lucae, S.; Holsboer, F.; Eder, M.; Uhr, M.; Ising, M.; Schmidt, M. V.; Rein, T.: Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans. PLOS MEDICINE 11 (11), e1001755 (2014)

Sun, M.; Hölter, S. M.; Stepan, J.; Garret, L.; Genius, J.; Kremmer, E.; Hrabe de Angelis, M.; Wurst, W.; Lie, D. C.; Bally-Cuif, L. et al.; Eder, M.; Rujescu, D.; Graw, J.: Crybb2 coding for beta B2-crystallin affects sensorimotor gating and hippocampal function. MAMMALIAN GENOME 24 (9-10), pp. 333 - 348 (2013)

Dine, J.; Ionescu, I. A.; Stepan, J.; Yen, Y.-C.; Holsboer, F.; Landgraf, R.; Eder, M.; Schmidt, U.: Identification of a Role for the Ventral Hippocampus in Neuropeptide S-Elicited Anxiolysis. PLOS ONE 8 (3), e60219 (2013)

Stepan, J.; Dine, J.; Fenzl, T.; Polta, S. A.; von Wolff, G.; Wotjak, C. T.; Eder, M.: Entorhinal theta-frequency input to the dentate gyrus trisynaptically evokes hippocampal CA1 LTP. Frontiers in Neural Circuits 6, 64 (2012)

Stepan, J.; Dine, J.; Wolff, G. v.; Zieglgänsberger, W.; Holsboer, F.; Eder, M.: High-speed voltage-sensitive dye imaging of neuronal activity propagation through limbic brain networks in vitro. Pharmacopsychiatry 44 (6), p. 308 - 308 (2011)

Wolff, G. v.; Avrabos, C.; Stepan, J.; Wurst, W.; Deussing, J. M.; Holsboer, F.; Eder, M.: Voltage-sensitive dye imaging demonstrates an enhancing effect of corticotropin-releasing hormone on neuronal activity propagation through the hippocampal formation. Journal of Psychiatric Research 45 (2), pp. 256 - 261 (2011)

Rein, T.; Stepan, J.; Balsevich, G.; Hartmann, J.; Genewsky, A.; Hafner, K.; Schmidt, M. V.; Eder, M.; Gassen, N.: Novel route to autophagy links to synaptic function and treatment options in depression. 30th Congress of the European College of Neuropsychopharmacology (ECNP), Paris, FRANCE, September 02, 2017 - September 05, 2017. EUROPEAN NEUROPSYCHOPHARMACOLOGY 27, S.05.04, p. S530 - S530 (2017)

Stepan, J.: Enhanced endocannabinoid signaling modulates neuronal network dynamics in the hippocampus. Dissertation, Ludwig-Maximilians-Universität München, München (2018)