Publikationen von Christian Kozany

Riebold, M.; Kozany, C.; Freiburger, L.; Sattler, M.; Buchfelder, M.; Hausch, F.; Stalla, G. K.; Páez-Pereda, M.: A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease. NATURE MEDICINE 21 (3), S. 276 - 280 (2015)

Pomplun, S.; Wang, Y.; Kirschner, A.; Kozany, C.; Bracher, A.; Hausch, F.: Rational Design and Asymmetric Synthesis of Potent and Neurotrophic Ligands for FK506-Binding Proteins (FKBPs). ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 54 (1), S. 345 - 348 (2015)

Gaali, S.; Kirschner, A.; Cuboni, S.; Hartmann, J.; Kozany, C.; Balsevich, G.; Namendorf, C.; Fernandez-Vizarra, P.; Sippel, C.; Zannas, A. S. et al.; Draenert, R.; Binder, E. B.; Almeida, O. F. X.; Ruehter, G.; Uhr, M.; Schmidt, M. V.; Touma, C.; Bracher, A.; Hausch, F.: Selective inhibitors of the FK506-binding protein 51 by induced fit. NATURE CHEMICAL BIOLOGY 11 (1), S. 33 - + (2015)

Hartmann, J.; Wagner, K. V.; Gaali, S.; Kirschner, A.; Kozany, C.; Ruhter, G.; Dedic, N.; Häusl, A. S.; Hoeijmakers, L.; Westerholz, S. et al.; Namendorf, C.; Gerlach, T.; Uhr, M.; Chen, A.; Deussing, J. M.; Holsboer, F.; Hausch, F.; Schmidt, M. V.: Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties. The Journal of neuroscience: the official journal of the Society for Neuroscience 35 (24), S. 9007 - 16 (2015)

Bracher, A.; Kozany, C.; Haehle, A.; Wild, P.; Zacharias, M.; Hausch, F.: Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge. JOURNAL OF MOLECULAR BIOLOGY 425 (22), S. 4134 - 4144 (2013)

Hausch, F.; Kozany, C.; Theodoropoulou, M.; Fabian, A.-K.: FKBPs and the Akt/mTOR pathway. CELL CYCLE 12 (15), S. 2366 - 2370 (2013)

Wang, Y.; Kirschner, A.; Fabian, A.-K.; Gopalakrishnan, R.; Kress, C.; Hoogeland, B.; Koch, U.; Kozany, C.; Bracher, A.; Hausch, F.: Increasing the Efficiency of Ligands for FK506-Binding Protein 51 by Conformational Control. JOURNAL OF MEDICINAL CHEMISTRY 56 (10), S. 3922 - 3935 (2013)

März, A. M.; Fabian, A.-K.; Kozany, C.; Bracher, A.; Hausch, F.: Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin. MOLECULAR AND CELLULAR BIOLOGY 33 (7), S. 1357 - 1367 (2013)

Fabian, A.-K.; März, A.; Neimanis, S.; Biondi, R. M.; Kozany, C.; Hausch, F.: InterAKTions with FKBPs - Mutational and Pharmacological Exploration. PLOS ONE 8 (2), e57508 (2013)

Gaali, S.; Gopalakrishnan, R.; Wang, Y.; Kozany, C.; Hausch, F.: The Chemical Biology of Immunophilin Ligands. Current Medicinal Chemistry 18 (35), S. 5355 - 5379 (2011)

Gräber, M.; Janczyk, W.; Sperl, B.; Elumalai, N.; Kozany, C.; Hausch, F.; Holak, T. A.; Berg, T.: Selective Targeting of Disease-Relevant Protein Binding Domains by O-Phosphorylated Natural Product Derivatives. ACS Chemical Biology 6 (10), S. 1008 - 1014 (2011)

Bracher, A.; Kozany, C.; Thost, A. K.; Hausch, F.: Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90. Pharmacopsychiatry 44 (6), S. 285 - 285 (2011)

Gaali, S.; Kozany, C.; Hoogeland, B.; Klein, M.; Hausch, F.: Development of fluorescence polarisation assays for the immunophilins FKBP51/52 and Cyp40. Pharmacopsychiatry 44 (6), S. 290 - 290 (2011)

Gopalakrishnan, R.; Kozany, C.; Hoogeland, B.; Bracher, A.; Hausch, F.: FKBP ligands. Pharmacopsychiatry 44 (6), S. 291 - 291 (2011)

Bracher, A.; Kozany, C.; Thost, A. K.; Hausch, F.: Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90. Acta Crystallographica Section D-Biological Crystallography 67, S. 549 - 559 (2011)

Gaali, S.; Kozany, C.; Hoogeland, B.; Klein, M.; Hausch, F.: Facile Synthesis of a Fluorescent Cyclosporin A Analogue To Study Cyclophilin 40 and Cyclophilin 18 Ligands. ACS Medicinal Chemistry Letters 1 (9), S. 536 - 539 (2010)

Kozany, C.; März, A.; Kress, C.; Hoogeland, B.; Hausch, F.: Development of specific inhibitors for the FK506 binding proteins 51 and 52. Pharmacopsychiatry 42 (5), S. 227 - 228 (2009)

Kozany, C.; Marz, A.; Kress, C.; Hausch, F.: Fluorescent Probes to Characterise FK506-Binding Proteins. ChemBioChem 10 (8), S. 1402 - 1410 (2009)

Laenger, A.; Lang-Rollin, I.; Kozany, C.; Zschocke, J.; Zimmermann, N.; Ruegg, J.; Holsboer, F.; Hausch, F.; Rein, T.: XAP2 inhibits glucocorticoid receptor activity in mammalian cells. FEBS Letters 583 (9), S. 1493 - 1498 (2009)

Kirmeier, T.; Fessler, B.; Wochnik-Veltrup, G.; Kozany, C.; Kimura, M.; Hausch, F.; Uhr, M.; Turck, C.; Holsboer, F.; Rein, T.: Proteomic search for intrcellular binding sites of antidepressants. Pharmacopsychiatry 40 (5), S. 210 - 210 (2007)