Publikationen von Alon Chen

Sen, P.; Ortiz, O.; Brivio, E.; Menegaz, D.; Sotillos Elliott, L.; Du, Y.; Ries, C.; Chen, A.; Wurst, W.; Lopez, J. P. et al.; Eder, M.; Deussing, J. M.: A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior. MOLECULAR PSYCHIATRY 30 (1), S. 97 - 110 (2025)

Murthy, B. K. B.; Somatakis, S.; Ulivi, A. F.; Klimmt, H.; Castello-Waldow, T. P.; Haynes, N.; Huettl, R. E.; Chen, A.; Attardo, A.: Arc-driven mGRASP highlights CA1 to CA3 synaptic engrams. FRONTIERS IN BEHAVIORAL NEUROSCIENCE 16, 1072571 (2023)

Brivio, E.; Kos, A.; Ulivi, A. F.; Karamihalev, S.; Reßle, A.; Stoffel, R.; Hirsch, D.; Stelzer, G.; Schmidt, M. V.; Lopez, J. P. et al.; Chen, A.: Sex shapes cell-type-specific transcriptional signatures of stress exposure in the mouse hypothalamus. CELL REPORTS 42 (8), 112874 (2023)

Kos, A.; Lopez, J. P.; Bordes, J.; De Donno, C.; Dine, J.; Brivio, E.; Karamihalev, S.; Luecken, M. D.; de Almeida-Correa, S.; Gasperoni, S. et al.; Dick, A.; Miranda, L.; Buettner, M.; Stoffel, R.; Flachskamm, C.; Theis, F. J.; Schmidt, M. V.; Chen, A.: Early life adversity shapes social subordination and cell type-specific transcriptomic patterning in the ventral hippocampus. SCIENCE ADVANCES 9 (48), eadj3793 (2023)

Lin, R.; Kos, A.; Lopez, J. P.; Dine, J.; Fiori, L. M.; Yang, J.; Ben-Efraim, Y. J.; Aouabed, Z.; Ibrahim, P.; Mitsuhashi, H. et al.; Wong, T. P.; Ibrahim, E. C.; Belzung, C.; Blier, P.; Farzan, F.; Frey, B. N.; Lam, R. W.; Milev, R.; Muller, D. J.; Parikh, S. V.; Soares, C.; Uher, R.; Nagy, C.; Mechawar, N.; Foster, J. A.; Kennedy, S. H.; Chen, A.; Turecki, G.: SNORD90 induces glutamatergic signaling following treatment with monoaminergic antidepressants. ELIFE 12, e85316 (2023)

Amitai, M.; Kaffman, S.; Kroizer, E.; Lebow, M.; Magen, I.; Benaroya-Milshtein, N.; Fennig, S.; Weizman, A.; Apter, A.; Chen, A.: Neutrophil to-lymphocyte and platelet-to-lymphocyte ratios as biomarkers for suicidal behavior in children and adolescents with depression or anxiety treated with selective serotonin reuptake inhibitors. BRAIN BEHAVIOR AND IMMUNITY 104, S. 31 - 38 (2022)

Brix, L. M.; Haeusl, A. S.; Toksoez, I.; Bordes, J.; van Doeselaar, L.; Engelhardt, C.; Narayan, S.; Springer, M.; Sterlemann, V.; Deussing, J. M. et al.; Chen, A.; Schmidt, M. V.: The co-chaperone FKBP51 modulates HPA axis activity and age-related maladaptation of the stress system in pituitary proopiomelanocortin cells. PSYCHONEUROENDOCRINOLOGY 138, 105670 (2022)

Chenani, A.; Weston, G.; Ulivi, A. F.; Castello-Waldow, T. P.; Huettl, R. E.; Chen, A.; Attardo, A.: Repeated stress exposure leads to structural synaptic instability prior to disorganization of hippocampal coding and impairments in learning. TRANSLATIONAL PSYCHIATRY 12 (1), 381 (2022)

Hausl, A. S.; Bajaj, T.; Brix, L.; Pohlmann, M. L.; Hafner, K.; De Angelis, M.; Nagler, J.; Dethloff, F.; Balsevich, G.; Schramm, K.-W. et al.; Giavalisco, P.; Chen, A.; Schmidt, M. V.; Gassen, N. C.: Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism. SCIENCE ADVANCES 8 (10), eabi4797 (2022)

Lopez, J. P.; Luecken, M. D.; Brivio, E.; Karamihalev, S.; Kos, A.; De Donno, C.; Benjamin, A.; Yang, H.; Dick, A. L. W.; Stoffel, R. et al.; Flachskamm, C.; Ressle, A.; Roeh, S.; Huettl, R. E.; Parl, A.; Eggert, C.; Novak, B.; Yan, Y.; Yeoh, K.; Lebar, M.; Hauger, B.; Harbich, D.; Schmid, B.; Di Giaimo, R.; Turck, C. W.; Schmidt, M. V.; Deussing, J. M.; Eder, M.; Dine, J.; Theis, F. J.; Chen, A.: Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2. NEURON 110 (14), S. 2283 - 2298.e9 (2022)

Ruat, J.; Genewsky, A. J.; Heinz, D. E.; Kaltwasser, S. F.; Canteras, N. S.; Czisch, M.; Chen, A.; Wotjak, C. T.: Why do mice squeak? Toward a better understanding of defensive vocalization. ISCIENCE 25 (7), 104657 (2022)

Vetrivel, S.; Zhang, R.; Engel, M.; Osswald, A.; Watts, D.; Chen, A.; Wielockx, B.; Sbiera, S.; Reincke, M.; Riester, A.: Characterization of Adrenal miRNA-Based Dysregulations in Cushing's Syndrome. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (14), 7676 (2022)

Furman, O.; Tsoory, M.; Chen, A.: Differential chronic social stress models in male and female mice. EUROPEAN JOURNAL OF NEUROSCIENCE (2021)

Ruat, J.; Hartmann, A.; Heinz, D. E.; Nemcova, P.; Stoffel, R.; Deussing, J. M.; Chen, A.; Wotjak, C. T.: CB1 receptors in corticotropin-releasing factor neurons selectively control the acoustic startle response in male mice. GENES BRAIN AND BEHAVIOR, e12775 (2021)

Benjamin, A.; Kuperman, Y.; Eren, N.; Rotkopf, R.; Amitai, M.; Rossman, H.; Shilo, S.; Meir, T.; Keshet, A.; Nuttman-Shwartz, O. et al.; Segal, E.; Chen, A.: Stress-related emotional and behavioural impact following the first COVID-19 outbreak peak. MOLECULAR PSYCHIATRY (2021)

Hausl, A. S.; Brix, L.; Hartmann, J.; Poehlmann, M. L.; Lopez, J. P.; Menegaz, D.; Brivio, E.; Engelhardt, C.; Roeh, S.; Bajaj, T. et al.; Rudolph, L.; Stoffel, R.; Hafner, K.; Goss, H. M.; Reul, J. M. H. M.; Deussing, J. M.; Eder, M.; Ressler, K. J.; Gassen, N. C.; Chen, A.; Schmidt, M. V.: The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice. MOLECULAR PSYCHIATRY (2021)

Bortolozzi, A.; Manashirov, S.; Chen, A.; Artigas, F.: Oligonucleotides as therapeutic tools for brain disorders: Focus on major depressive disorder and Parkinson's disease. PHARMACOLOGY & THERAPEUTICS 227, 107873 (2021)

Dick, A.; Chen, A.: The role of TET proteins in stress-induced neuroepigenetic and behavioural adaptations. NEUROBIOLOGY OF STRESS 15, 100352 (2021)

Lopez, J. P.; Brivio, E.; Santambrogio, A.; De Donno, C.; Kos, A.; Peters, M.; Rost, N.; Czamara, D.; Brueckl, T.; Roeh, S. et al.; Poehlmann, M. L.; Engelhardt, C.; Ressle, A.; Stoffel, R.; Tontsch, A.; Villamizar, J. M.; Reincke, M.; Riester, A.; Sbiera, S.; Fassnacht, M.; Mayberg, H. S.; Craighead, W. E.; Dunlop, B. W.; Nemeroff, C. B.; Schmidt, M. V.; Binder, E. B.; Theis, F. J.; Beuschlein, F.; Andoniadou, C. L.; Chen, A.: Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation. SCIENCE ADVANCES 7 (5), eabe4497 (2021)

Mevorach, T.; Taler, M.; Dar, S.; Lebow, M.; Sapir, I. S.; Rotkopf, R.; Apter, A.; Fennig, S.; Chen, A.; Weizman, A. et al.; Amitai, M.: The relationship between the plasma proinflammatory cytokine levels of depressed/anxious children and their parents. SCIENTIFIC REPORTS 11 (1), 11798 (2021)